Andrew E. Sloan Lab

Innovative Neuro-Oncology Research

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Andrew E. Sloan

Professor & Vice Chairman, Department of Neurosurgery
Peter D. Cristal Chair of Neurosurgical Oncology
Director, Brain Tumor & Neuro-Oncology Center
Director, Center of Excellence for Translational Neuro-Oncology
Distinguished Surgeon & Senior Staff Neurosurgeon
University Hospitals-Cleveland Medical Center &  Seidman Cancer Center, Case Comprehensive Cancer Center

Dr. Sloan focuses on clinical and translational approaches to the treatment of malignant brain tumors and has been funded by NIH, NCI, the Ohio Third Frontier organization, the American Society of Clinical Oncology (ASCO), The American Brain Tumor Association (ABTA), the Adult Brain Tumor Consortium (ABTC), Howard Hughes Medical Institute (HHMI), and other national organizations, as well as several pharmaceutical companies.  He has more than 210 peer-reviewed publications, 6 US patents and INDs, and more than 600 invited presentations, and sits on the editorial boards of several neurosurgical and general medical journals.

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Team Members

 
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Amber Kerstetter-Fogle, Ph.D.

Amber is a senior research associate and lab manager.  She has over 20 years of experience in neuroscience and has been involved with neuro-oncology research for the past 11 years.  She is interested in the tumor microenvironment.    Amber obtained her B.S. from Muskingum University in 2002 and graduated with her Master’s degree in biology from the University of Akron in 2004.  She completed her Ph.D. dissertation in 2010 in the lab of Robert H. Miller at Case Western Reserve University studying the effect of chemokines in Multiple Sclerosis progression.  She joined Andrew Sloan’s laboratory in 2011.  Amber is currently pursuing a Master’s degree in the Clinical Research Scholars program at CWRU and is studying the role of clinical biomarkers in assessing prognosis of disease in GBM.  Amber enjoys spending time with her husband and two children and her friends.  She enjoys volunteering at school functions, reading, exercising, hiking and camping.

Key Publications

We are proud to showcase the results of research undertaken by members of our interdisciplinary Scientific Research Laboratory. Our work and findings have been published in a number of prestigious publications in our field.

A Liquid Biopsy to Assess Brain Tumor Recurrence: Presence of Circulating Mo-MDSC and CD14+ VNN2+ Myeloid Cells as Biomarkers that Distinguish Brain Metastasis from Radiation Necrosis Following Stereotactic Radiosurgery

21 August 2020

Neurosurgery  88(1): E67-E72

Proteins Inform Survival-Based Differences in Patients with Glioblastoma

17 March 2020

Neuro-Oncology Advances 2(1) 1-11

Plant Virus-Like Particle In Situ Vaccine for Intracranial Glioma Immunotherapy

10 April 2019

Cancers (Basel)  11(4): 515

The Ratio of HLA-DR and VNN2+ Expression on CD14+ Myeloid Derived Suppressor Cells Can Distinguish Glioblastoma from Radiation Necrosis Patients

27 May 2017

Neurooncol 134(1): 189-196

Targeting Glioma Stem Cells Through Combined BMI1 and EZH2 Inhibition

9 October 2017

Nature Medicine  23: 1352-1361